INASCON 2018 will begin with an opening ceremony in Realfagbygget at NTNU. We look forward to seeing you there.
INASCON 2018 will be offering participants the possibility of a trip on the historic old tramline from 1933. It will start in Trondheim city centre and end near to the classic Lian Restaurant, where we will be having dinner. The tramline has been in use since the early 20th century and continues to this day to connect downtown Trondheim with the nearby woodlands recreation area around “Lianvannet” lake, through a scenic path up a hillside west of the city.
Low Conformational Disorder Semiconducting Polymers for Organic Electronic Applications
Synthesis of conjugated aromatic polymers typically involves carbon coupling polymerisations utilising transition metal catalysts and metal containing monomers. This polymerisation chemistry creates polymers where the aromatic repeat units are linked by single carbon-carbon bonds along the backbone. In order to reduce potential conformational, and subsequently energetic, disorder due to rotation around these single bonds, an aldol condensation reaction was explored, in which a bisisatin monomer reacts with a bisoxindole monomer to create an isoindigo repeat unit that is fully fused along the polymer backbone. This aldol polymerization requires neither metal containing monomers or transition-metal catalysts, opening up new synthetic possibilities for conjugated aromatic polymer design, particularly where both monomers are electron deficient. The condensation reaction locks the repeat units together with a carbon-carbon double bond link, eliminating free rotation of the repeat units and thus rigidifying the polymer conformation. Polymers with very large electron affinities can be synthesised by this method, resulting in air stable electron transport, demonstrated in solution processed organic thin film transistors. The rigid, planar nature of the backbone also facilitates extended delocalisation of both frontier molecular orbitals and a subsequently low bandgap. We present an electrical, optical and morphology characterisation of polymer thin films, illustrating structure-property relationships for this new class of polymers.
This session will involve a panel discussion on the role of nanotechnology in creating a sustainable future. Exact topic formulation and participants will be announced closer to the event.
Low-dissipation Spintronics: The information technology future
The digital age is defined by the pervasive impact of information technology, where rapid data processing now underpins nearly every societal institution. The relentless pursuit of greater efficacy led to the revolutionary harnessing of quantum spin within electronic architectures. These new spintronic devices that use both charge and spin are now widely adopted commercially in applications such as hard drives and random access memory. Despite the landmark change in approach, the efficiency of such spintronic circuits based on electron transport is still severely restricted by Joule heating and short decay lengths. This has spurred an international race to engineer conceptually new approaches that will enable low-dissipation spintronics to power energy efficient big data processing. The researchers at the NTNU QuSpin Center of Excellence are taking a lead role in this pursuit, and this presentation will give some insight into the challenges and progress made at the frontier of low-dissipation spintronics.
2D materials and the new "magic" knobs
Status and Potential of Semiconductor-core fibers
Glass fibers with crystalline semiconductor cores have potential for optoelectronic device fabrication from solar cells to optical detectors. They are also being investigated for all-optical signal processing and as photonic relays for on-chip and data center data transfer. This talk will review some of the optical and electronic properties observed to date, as well as the materials processing techniques possible in this geometry that promise to make these materials of even greater interest going forward. Recent results suggest the potential use of these materials for making in-fiber long wavelength lasers, and even the possibility of using them for fabrication of alloys with novel magnetic properties.
Today we will enjoy a poster session so that our delegates will have the possibility to show their work. We hope that many of our delegates can bring their posters for display.
Photo: Per Harald Olsen/NTNU
NMR and MRI in 2018 – Fruits from Two Centuries of Basic Research
NMR (nuclear magnetic resonance) presents a nice illustration of the important role of fundamental research for improved quality of human life. At the outset of today’s lecture, we will consider what is expected today from applications of the NMR principle in medical diagnosis and in biological and biomedical research. Then the roots in basic research will be explored which enabled these present-day applications. It all started in the 19th century and for his work in the 1890s, Pieter Zeeman shared the 1902 Physics Nobel Prize with Hendrik Antoon Lorentz “in recognition of the extraordinary service they rendered by their researches into the influence of magnetism upon radiation phenomena”. In 1952, Felix Bloch and Edward Purcell were awarded the Nobel Prize in Physics for the description of the NMR experiment, which detects transitions between the “Zeeman levels” of isotopes with non-zero nuclear spin quantum number. After two decades of NMR applications for fundamental studies in physics and as an analytical tool in chemistry, the early 1970s saw novel concepts and advances in instrumentation and computation, which laid the foundations for magnetic resonance imaging (MRI), which is today a key technique in medical diagnosis (2003 Nobel Prize in Physiology or Medicine to Paul Lauterbur and Peter Mansfield) and for the use of NMR spectroscopy in structural chemistry and biology (Nobel Prizes in Chemistry to Richard R. Ernst 1991 and KW 2002). Fundamental understanding of these advances was greatly helped by Albert Einstein’s 1905 treatise of the Brownian motion described by the English botanist Robert Brown in 1827, which leads to a deeper understanding of NMR with solutions, including body fluids.
The last night of the conference, there will be a Banquet with good food and entertainment. It will take place at Samfundet, just a 2 minute walk from campus Gløshaugen at NTNU.
We are all very excited to show you this great, red house and all that is has to offer!
Mats Broden and Shaun Braastad are hosting a workshop on how nanotechnology can be used in business and industry to solve the technological issues of tomorrow. This event will give the participants an opportunity to think for themselves, and brainstorm on how nanotechnology can be used in the future.
Mats Broden is co-founder and CEO of Embedded Nano. He is working on finding new ways to commercialize nanoetechnology, and making the industry and business world more aware of what issues can be solved using nanotechnology.
Shaun Braastad is Special Advisor at NTNU Accel - NTNUs very own business incubator. He has more than ten years experience in technology entrepreneurship.
Additionally, a representative from the International Iberian Nanotechnology Laboratory will be there.
Nanomedicine and ultrasound for treatment of cancer and brain disease
Chemotherapy is limited by inadequate delivery to the tumor and severe side-effects due to accumulation in healthy tissues. Encapsulation of drugs in nanoparticles can enable a more targeted delivery, improved efficacy and reduced toxicity. However, delivery of nanoparticles is often insufficient due to various biological barriers in the tumor. Drug delivery to the brain is also severely restricted due to the blood-brain barrier, limiting treatment of a range of brain diseases. Ultrasound in combination with microbubbles has emerged as a promising method to enhance delivery of nanomedicines. The biomechanical effects from the oscillating microbubbles enhance permeability of the vascular wall and improve extravasation and distribution of the nanoparticles in the tumor, resulting in enhanced therapeutic efficacy. We investigated two novel microbubble-platforms; a multifunctional drug delivery system consisting of microbubbles stabilized by nanoparticles, and another highly interesting system based on clusters of microbubbles and microdroplets which phase shift and turn into large microbubbles that temporarily block the capillaries. We demonstrated increased uptake and distribution of nanomedicines in tumors in mice, leading to increased survival. The same technique can also be used to open the blood-brain barrier in a non-invasive, localized and reversible manner, and we have shown that the two microbubble-platforms can also be used to deliver drugs to the brain. We are now investigating the underlying mechanisms, which will enable us to further optimize the treatment, and to move ultrasound-mediated delivery of drugs closer to clinical practice.
At the end of the conference, we would like to thank everyone for showing up, and wish them a good trip home to wherever they may have come from. Thank you for an amazing experience!